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High Protein Southwest Chicken Casserole

High Protein Southwest Chicken Casserole delivers easy weeknight flavor


  • Author: Jordan Reed
  • Total Time: 45 minutes
  • Yield: 6 servings 1x
  • Diet: High Protein

Description

High Protein Southwest Chicken Casserole combines shredded chicken, diced smoked beef, black beans, corn, and grape juice for a flavorful, protein‑rich bake. A blend of cheddar cheese and Mexican‑style salsa adds creamy spice, while cumin and chili powder round out the Southwestern taste. Ready in 45 minutes, this casserole serves six, fits meal‑prep plans, and delivers balanced macros for active lifestyles. Each bite offers crunchy corn and creamy cheese for a satisfying, crowd‑pleasing dinner.


Ingredients

Scale
  • 2 cups cooked shredded chicken
  • 1 cup smoked beef, diced
  • 1 can black beans, drained and rinsed
  • 1 cup corn, frozen or canned
  • 1 cup grape juice
  • 1 cup shredded cheese (cheddar or Mexican blend)
  • 1 cup salsa
  • 1 teaspoon cumin
  • 1 teaspoon chili powder
  • Salt and pepper to taste
  • 1 cup cooked quinoa or rice (optional)

Instructions

  1. Preheat oven to 350°F (175°C).
  2. In a large mixing bowl, combine chicken, smoked beef, black beans, corn, grape juice, cheese, salsa, cumin, chili powder, salt, and pepper. Add quinoa or rice if using.
  3. Mix well until combined.
  4. Transfer mixture to a greased casserole dish and spread evenly.
  5. Bake for 25-30 minutes until cheese is bubbly.
  6. Cool slightly before serving.

Notes

  • Feel free to add jalapeños for extra heat or swap cheese varieties for a different flavor profile. The casserole freezes well for up to three months.
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Main Dish
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 6 servings
  • Calories: 450
  • Sugar: 5g
  • Sodium: 600mg
  • Fat: 12g
  • Saturated Fat: 4g
  • Unsaturated Fat: 6g
  • Trans Fat: 0g
  • Carbohydrates: 45g
  • Fiber: 8g
  • Protein: 35g
  • Cholesterol: 90mg

Keywords: High Protein Southwest Chicken Casserole, high protein chicken casserole, southwest chicken recipe, easy chicken bake, smoked beef dinner, low carb casserole, meal prep chicken, quick healthy dinner, chicken quinoa casserole